Selection for Neutralization Resistance of the Simian/Human Immunodeficiency Virus SHIV(SF33A) Variant In Vivo by Virtue of Sequence Changes in the Extracellular Envelope Glycoprotein That Modify N-Linked Glycosylation

We previously reported on the in vivo adaptation of an infectious molecular simian/human immunodeficiency virus (SHIV) clone, SHIV(SF33), into a pathogenic biologic viral variant, designated SHIV(SF33A). In the present study, we show that SHIV(SF33A) is resistant to neutralization by human immunodef...

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Main Authors: Cheng-Mayer, Cecilia, Brown, Amanda, Harouse, Janet, Luciw, Paul A., Mayer, Allen J.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
主題:
Pathogenesis and Immunity
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC112584/
https://ncbi.nlm.nih.gov/pubmed/10364275
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