Quantile-Based Permutation Thresholds for Quantitative Trait Loci Hotspots

Quantitative trait loci (QTL) hotspots (genomic locations affecting many traits) are a common feature in genetical genomics studies and are biologically interesting since they may harbor critical regulators. Therefore, statistical procedures to assess the significance of hotspots are of key importan...

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Autors principals: Neto, Elias Chaibub, Keller, Mark P., Broman, Andrew F., Attie, Alan D., Jansen, Ritsert C., Broman, Karl W., Yandell, Brian S.
Format: Artigo
Idioma:Inglês
Publicat: Genetics Society of America 2012
Matèries:
Investigations
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416013/
https://ncbi.nlm.nih.gov/pubmed/22661325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.139451
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