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Treatment of the X chromosome in mapping multiple quantitative trait loci

Statistical methods to map quantitative trait loci (QTL) often neglect the X chromosome and may focus exclusively on autosomal loci. But the X chromosome often requires special treatment: sex and cross-direction covariates may need to be included to avoid spurious evidence of linkage, and the X chro...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Tran, Quoc, Broman, Karl W
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8022961/
https://ncbi.nlm.nih.gov/pubmed/33604671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/g3journal/jkab005
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