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Quantile-Based Permutation Thresholds for Quantitative Trait Loci Hotspots

Quantitative trait loci (QTL) hotspots (genomic locations affecting many traits) are a common feature in genetical genomics studies and are biologically interesting since they may harbor critical regulators. Therefore, statistical procedures to assess the significance of hotspots are of key importan...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Neto, Elias Chaibub, Keller, Mark P., Broman, Andrew F., Attie, Alan D., Jansen, Ritsert C., Broman, Karl W., Yandell, Brian S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Genetics Society of America 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416013/
https://ncbi.nlm.nih.gov/pubmed/22661325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.139451
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