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Dynamic Mutation–Selection Balance as an Evolutionary Attractor
The vast majority of mutations are deleterious and are eliminated by purifying selection. Yet in finite asexual populations, purifying selection cannot completely prevent the accumulation of deleterious mutations due to Muller’s ratchet: once lost by stochastic drift, the most-fit class of genotypes...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Genetics Society of America
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416009/ https://ncbi.nlm.nih.gov/pubmed/22661327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.141291 |
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