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Fluctuations of Fitness Distributions and the Rate of Muller’s Ratchet
The accumulation of deleterious mutations is driven by rare fluctuations that lead to the loss of all mutation free individuals, a process known as Muller’s ratchet. Even though Muller’s ratchet is a paradigmatic process in population genetics, a quantitative understanding of its rate is still lacki...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416007/ https://ncbi.nlm.nih.gov/pubmed/22649084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.141325 |
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