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Distribution of the Fittest Individuals and the Rate of Muller's Ratchet in a Model with Overlapping Generations

Muller's ratchet is a paradigmatic model for the accumulation of deleterious mutations in a population of finite size. A click of the ratchet occurs when all individuals with the least number of deleterious mutations are lost irreversibly due to a stochastic fluctuation. In spite of the simplic...

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Bibliografiske detaljer
Main Authors: Metzger, Jakob J., Eule, Stephan
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820511/
https://ncbi.nlm.nih.gov/pubmed/24244123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003303
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