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Dynamic Mutation–Selection Balance as an Evolutionary Attractor
The vast majority of mutations are deleterious and are eliminated by purifying selection. Yet in finite asexual populations, purifying selection cannot completely prevent the accumulation of deleterious mutations due to Muller’s ratchet: once lost by stochastic drift, the most-fit class of genotypes...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Genetics Society of America
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3416009/ https://ncbi.nlm.nih.gov/pubmed/22661327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.141291 |
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