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A Computationally Optimized Hemagglutinin Virus-Like Particle Vaccine Elicits Broadly Reactive Antibodies that Protect Nonhuman Primates from H5N1 Infection

BACKGROUND: Highly pathogenic H5N1 avian influenza viruses continue to spread via waterfowl, causing lethal infections in humans. Vaccines can prevent the morbidity and mortality associated with pandemic influenza isolates. Predicting the specific isolate that may emerge from the 10 different H5N1 c...

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Detaylı Bibliyografya
Asıl Yazarlar: Giles, Brendan M., Crevar, Corey J., Carter, Donald M., Bissel, Stephanie J., Schultz-Cherry, Stacey, Wiley, Clayton A., Ross, Ted M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415819/
https://ncbi.nlm.nih.gov/pubmed/22448011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis232
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