Preserved Function of Regulatory T Cells in Chronic HIV-1 Infection Despite Decreased Numbers in Blood and Tissue

Regulatory T cells (Tregs) are potent immune modulators, but their role in human immunodeficiency virus type 1 (HIV-1) pathogenesis remains poorly understood. We performed a detailed analysis of the frequency and function of Tregs in a large cohort of HIV-1–infected individuals and HIV-1 negative co...

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Autores principales: Angin, Mathieu, Kwon, Douglas S., Streeck, Hendrik, Wen, Fang, King, Melanie, Rezai, Ashley, Law, Kenneth, Hongo, Tomoyuki C., Pyo, Augustine, Piechocka-Trocha, Alicja, Toth, Ildiko, Pereyra, Florencia, Ghebremichael, Musie, Rodig, Scott J., Milner, Danny A., Richter, James M., Altfeld, Marcus, Kaufmann, Daniel E., Walker, Bruce D., Addo, Marylyn M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2012
Materias:
Major Articles and Brief Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415814/
https://ncbi.nlm.nih.gov/pubmed/22427677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jis236
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