Dysregulated Tim-3 expression on natural killer cells is associated with increased Galectin-9 levels in HIV-1 infection

BACKGROUND: Natural killer (NK) cells constitutively express high levels of Tim-3, an immunoregulatory molecule recently proposed to be a marker for mature and functional NK cells. Whether HIV-1 infection modulates the expression of Tim-3 on NK cells, or the levels of its ligand Galectin-9 (Gal-9),...

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Autors principals: Jost, Stephanie, Moreno-Nieves, Uriel Y, Garcia-Beltran, Wilfredo F, Rands, Keith, Reardon, Jeff, Toth, Ildiko, Piechocka-Trocha, Alicja, Altfeld, Marcus, Addo, Marylyn M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3750478/
https://ncbi.nlm.nih.gov/pubmed/23866914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-74
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