Regulatory T Cells Expanded from HIV-1-Infected Individuals Maintain Phenotype, TCR Repertoire and Suppressive Capacity

While modulation of regulatory T cell (Treg) function and adoptive Treg transfer are being explored as therapeutic modalities in the context of autoimmune diseases, transplantation and cancer, their role in HIV-1 pathogenesis remains less well defined. Controversy persists regarding their beneficial...

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Main Authors: Angin, Mathieu, Klarenbeek, Paul L., King, Melanie, Sharma, Siddhartha M., Moodley, Eshia S., Rezai, Ashley, Piechocka-Trocha, Alicja, Toth, Ildiko, Chan, Andrew T., Goulder, Philip J., Ndung'u, Thumbi, Kwon, Douglas S., Addo, Marylyn M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911933/
https://ncbi.nlm.nih.gov/pubmed/24498287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0086920
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