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Functional consequences of human airway smooth muscle phenotype plasticity

BACKGROUND AND PURPOSE: Airway smooth muscle (ASM) phenotype plasticity, characterized by reversible switching between contractile and proliferative phenotypes, is considered to contribute to increased ASM mass and airway hyper-responsiveness in asthma. Further, increased expression of collagen I ha...

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Detalhes bibliográficos
Main Authors: Dekkers, Bart GJ, Bos, I Sophie T, Zaagsma, Johan, Meurs, Herman
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415660/
https://ncbi.nlm.nih.gov/pubmed/22053853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2011.01773.x
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