The Immunobiology of Colitis and Cholangitis in IL-23p19 and IL-17A Deleted dnTGFβRII Mice

dnTGFβRII mice, expressing a dominant negative form of TGFβ receptor II under control of the CD4 promoter, develop autoimmune colitis and cholangitis . We previously observed that deficiency in IL-12p40 led to a marked diminution of inflammation in both the colon and the liver. To distinguish whethe...

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Main Authors: Ando, Yugo, Yang, Guo-Xiang, Tsuda, Masanobu, Kawata, Kazuhito, Zhang, Weici, Nakajima, Takahiko, Tsuneyama, Koichi, Leung, Patrick, Lian, Zhe-Xiong, Okazaki, Kazuichi, Ridgway, William M., Norman, Gary L., Ansari, Aftab A., He, Xiao-Song, Coppel, Ross L., Gershwin, M. Eric
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415593/
https://ncbi.nlm.nih.gov/pubmed/22532156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25803
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