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Adoptive transfer of CD8(+) T cells from dnTGFβRII mice induces autoimmune cholangitis into Rag1(−/−) mice

We recently reported that mice with a T cell-restricted expression of a dominant negative (dn) form of the TGF-β receptor type II spontaneously develop autoimmune cholangitis that resembles human PBC, including antimitochondrial antibodies and extensive portal CD4(+) and CD8(+) lymphocytic infiltrat...

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Detalhes bibliográficos
Main Authors: Yang, Guo-Xiang, Lian, Zhe-Xiong, Chuang, Ya-Hui, Moritoki, Yuki, Lan, Ruth Y., Wakabayashi, Kanji, Ansari, Aftab A., Flavell, Richard A., Ridgway, William M., Coppel, Ross L., Tsuneyama, Koichi, Mackay, Ian R., Gershwin, M. Eric
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749317/
https://ncbi.nlm.nih.gov/pubmed/18452147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22226
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