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Thiamin pyrimidine biosynthesis in Candida albicans: a remarkable reaction between histidine and pyridoxal phosphate

In S. cerevisiae the thiamin pyrimidine is formed from histidine and pyridoxal phosphate. The origin of all of the pyrimidine atoms has been determined using labeling studies and suggests that the pyrimidine is formed using remarkable chemistry that is without chemical or biochemical precedent. Here...

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Detalhes bibliográficos
Main Authors: Lai, Rung-Yi, Huang, Siyu, Fenwick, Michael Kenneth, Hazra, Amrita, Zhang, Yang, Rajashankar, Kanagalaghatta, Philmus, Benjamin, Kinsland, Cynthia, Sanders, Jennie Mansell, Ealick, Steven E., Begley, Tadhg P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415583/
https://ncbi.nlm.nih.gov/pubmed/22568620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302474a
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