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Thiamin pyrimidine biosynthesis in Candida albicans: a remarkable reaction between histidine and pyridoxal phosphate

In S. cerevisiae the thiamin pyrimidine is formed from histidine and pyridoxal phosphate. The origin of all of the pyrimidine atoms has been determined using labeling studies and suggests that the pyrimidine is formed using remarkable chemistry that is without chemical or biochemical precedent. Here...

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Autors principals: Lai, Rung-Yi, Huang, Siyu, Fenwick, Michael Kenneth, Hazra, Amrita, Zhang, Yang, Rajashankar, Kanagalaghatta, Philmus, Benjamin, Kinsland, Cynthia, Sanders, Jennie Mansell, Ealick, Steven E., Begley, Tadhg P.
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415583/
https://ncbi.nlm.nih.gov/pubmed/22568620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja302474a
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