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Enantioselective α-Vinylation of Aldehydes Via the Synergistic Combination of Copper and Amine Catalysis

The enantioselective α-vinylation of aldehydes using vinyl iodonium triflate salts has been accomplished via the synergistic combination of copper and chiral amine catalysis. These mild catalytic conditions provide a direct route for the enantioselective construction of enolizable α-formyl vinylic s...

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Detalhes bibliográficos
Main Authors: Skucas, Eduardas, MacMillan, David W. C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415571/
https://ncbi.nlm.nih.gov/pubmed/22616631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja303116v
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