Exome Sequencing Followed by Large-Scale Genotyping Suggests a Limited Role for Moderately Rare Risk Factors of Strong Effect in Schizophrenia

Schizophrenia is a severe psychiatric disorder with strong heritability and marked heterogeneity in symptoms, course, and treatment response. There is strong interest in identifying genetic risk factors that can help to elucidate the pathophysiology and that might result in the development of improv...

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Main Authors: Need, Anna C., McEvoy, Joseph P., Gennarelli, Massimo, Heinzen, Erin L., Ge, Dongliang, Maia, Jessica M., Shianna, Kevin V., He, Min, Cirulli, Elizabeth T., Gumbs, Curtis E., Zhao, Qian, Campbell, C. Ryan, Hong, Linda, Rosenquist, Peter, Putkonen, Anu, Hallikainen, Tero, Repo-Tiihonen, Eila, Tiihonen, Jari, Levy, Deborah L., Meltzer, Herbert Y., Goldstein, David B.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2012
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415532/
https://ncbi.nlm.nih.gov/pubmed/22863191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2012.06.018
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