Cardiac-Specific Over-Expression of Epidermal Growth Factor Receptor 2 (ErbB2) Induces Pro-Survival Pathways and Hypertrophic Cardiomyopathy in Mice

BACKGROUND: Emerging evidence shows that ErbB2 signaling has a critical role in cardiomyocyte physiology, based mainly on findings that blocking ErbB2 for cancer therapy is toxic to cardiac cells. However, consequences of high levels of ErbB2 activity in the heart have not been previously explored....

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Sysa-Shah, Polina, Xu, Yi, Guo, Xin, Belmonte, Frances, Kang, Byunghak, Bedja, Djahida, Pin, Scott, Tsuchiya, Noriko, Gabrielson, Kathleen
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415416/
https://ncbi.nlm.nih.gov/pubmed/22912742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042805
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky