Echocardiographic Characterization of a Murine Model of Hypertrophic Obstructive Cardiomyopathy Induced by Cardiac-specific Overexpression of Epidermal Growth Factor Receptor 2

Although rare, hypertrophic cardiomyopathy (HCM) with midventricular obstruction is often associated with severe symptoms and complications. None of the existing HCM animal models display this particular phenotype. Our group developed a mouse line that overexpresses the ErbB2 receptor (ErbB2(tg)) in...

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Publicat a:Comp Med
Autors principals: Sørensen, Lars L, Bedja, Djahida, Sysa-Shah, Polina, Liu, Hongyun, Maxwell, Amanda, Yi, Xu, Pozios, Iraklis, Olsen, Niels T, Abraham, Theodore P, Abraham, Roselle, Gabrielson, Kathleen
Format: Artigo
Idioma:Inglês
Publicat: American Association for Laboratory Animal Science 2016
Matèries:
Mouse Models
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983168/
https://ncbi.nlm.nih.gov/pubmed/27538857
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