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Dissecting the Gene Network of Dietary Restriction to Identify Evolutionarily Conserved Pathways and New Functional Genes

Dietary restriction (DR), limiting nutrient intake from diet without causing malnutrition, delays the aging process and extends lifespan in multiple organisms. The conserved life-extending effect of DR suggests the involvement of fundamental mechanisms, although these remain a subject of debate. To...

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Библиографические подробности
Главные авторы: Wuttke, Daniel, Connor, Richard, Vora, Chintan, Craig, Thomas, Li, Yang, Wood, Shona, Vasieva, Olga, Shmookler Reis, Robert, Tang, Fusheng, de Magalhães, João Pedro
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415404/
https://ncbi.nlm.nih.gov/pubmed/22912585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002834
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