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Chromosomal periodicity of evolutionarily conserved gene pairs

Chromosomes are compacted hundreds of times to fit in the cell, packaged into dynamic folds whose structures are largely unknown. Here, we examine patterns in gene locations to infer large-scale features of bacterial chromosomes. Specifically, we analyzed >100 genomes and identified thousands of...

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Autors principals: Wright, Matthew A., Kharchenko, Peter, Church, George M., Segrè, Daniel
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1890563/
https://ncbi.nlm.nih.gov/pubmed/17563360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610776104
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