Mutation Patterns of 16 Genes in Primary and Secondary Acute Myeloid Leukemia (AML) with Normal Cytogenetics

Acute myeloid leukemia patients with normal cytogenetics (CN-AML) account for almost half of AML cases. We aimed to study the frequency and relationship of a wide range of genes previously reported as mutated in AML (ASXL1, NPM1, FLT3, TET2, IDH1/2, RUNX1, DNMT3A, NRAS, JAK2, WT1, CBL, SF3B1, TP53,...

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Detalhes bibliográficos
Main Authors: Fernandez-Mercado, Marta, Yip, Bon Ham, Pellagatti, Andrea, Davies, Carwyn, Larrayoz, María José, Kondo, Toshinori, Pérez, Cristina, Killick, Sally, McDonald, Emma-Jane, Odero, María Dolores, Agirre, Xabier, Prósper, Felipe, Calasanz, María José, Wainscoat, James S., Boultwood, Jacqueline
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415392/
https://ncbi.nlm.nih.gov/pubmed/22912701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0042334
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