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The Role of Conformational Flexibility on Protein Supercharging in Native Electrospray Ionization
Effects of covalent intramolecular bonds, either native disulfide bridges or chemical crosslinks, on ESI supercharging of proteins from aqueous solutions were investigated. Chemically modifying cytochrome c with up to seven crosslinks or ubiquitin with up to two crosslinks did not affect the average...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3415327/ https://ncbi.nlm.nih.gov/pubmed/21399817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c1cp20277d |
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