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Mitochondria DNA Replication and DNA Methylation in the Metabolic Memory Associated with Continued Progression of Diabetic Retinopathy

PURPOSE. Diabetic retinopathy fails to halt after cessation of hyperglycemic insult, and a vicious cycle of mitochondria damage continues. The aim of our study was to investigate the effect of termination of hyperglycemia on retinal mtDNA replication, and elucidate the mechanism responsible for the...

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書誌詳細
主要な著者: Tewari, Shikha, Zhong, Qing, Santos, Julia M, Kowluru, Renu A
フォーマット: Artigo
言語:Inglês
出版事項: The Association for Research in Vision and Ophthalmology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3415280/
https://ncbi.nlm.nih.gov/pubmed/22743328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.12-9732
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