Llwytho...

Role of β-Hairpin Formation in Aggregation: The Self-Assembly of the Amyloid-β(25–35) Peptide

The amyloid-β(25–35) peptide plays a key role in the etiology of Alzheimer's disease due to its extreme toxicity even in the absence of aging. Because of its high tendency to aggregate and its low solubility in water, the structure of this peptide is still unknown. In this work, we sought to un...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Larini, Luca, Shea, Joan-Emma
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414875/
https://ncbi.nlm.nih.gov/pubmed/22947874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.027
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