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Measuring Molecular Motor Forces In Vivo: Implications for Tug-of-War Models of Bidirectional Transport

Molecular motor proteins use the energy released from ATP hydrolysis to generate force and haul cargoes along cytoskeletal filaments. Thus, measuring the force motors generate amounts to directly probing their function. We report on optical trapping methodology capable of making precise in vivo stal...

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Bibliographic Details
Main Authors: Leidel, Christina, Longoria, Rafael A., Gutierrez, Franciso Marquez, Shubeita, George T.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414874/
https://ncbi.nlm.nih.gov/pubmed/22947865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.038
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