Measuring Molecular Motor Forces In Vivo: Implications for Tug-of-War Models of Bidirectional Transport

Molecular motor proteins use the energy released from ATP hydrolysis to generate force and haul cargoes along cytoskeletal filaments. Thus, measuring the force motors generate amounts to directly probing their function. We report on optical trapping methodology capable of making precise in vivo stal...

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Hauptverfasser: Leidel, Christina, Longoria, Rafael A., Gutierrez, Franciso Marquez, Shubeita, George T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Molecular Machines, Motors, and Nanoscale Biophysics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414874/
https://ncbi.nlm.nih.gov/pubmed/22947865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.038
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