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Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

Intracellular transport is based on molecular motors that pull cargos along cytoskeletal filaments. One motor species always moves in one direction, e.g., conventional kinesin moves to the microtubule plus end, whereas cytoplasmic dynein moves to the microtubule minus end. However, many cellular car...

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Detalhes bibliográficos
Main Authors: Müller, Melanie J. I., Klumpp, Stefan, Lipowsky, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290779/
https://ncbi.nlm.nih.gov/pubmed/18347340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0706825105
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