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Spontaneous inflammatory pain model from a mouse line with N-ethyl-N-nitrosourea mutagenesis

BACKGROUND: N-ethyl-N-nitrosourea mutagenesis was used to induce a point mutation in C57BL/6 J mice. Pain-related phenotype screening was performed in 915 G3 mice. We report the detection of a heritable recessive mutant in meiotic recombinant N1F1 mice that caused an abnormal pain sensitivity phenot...

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Detalhes bibliográficos
Main Authors: Chen, Tsung-Chieh, Wu, José Jiun-Shian, Chang, Wei-Pang, Hsu, Ping-Ning, Hsieh, Sung-Tsang, Shyu, Bai-Chuang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414809/
https://ncbi.nlm.nih.gov/pubmed/22646813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1423-0127-19-55
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