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N-Ethyl-N-Nitrosourea Mutagenesis: Boarding the Mouse Mutant Express
In the mouse, random mutagenesis with N-ethyl-N-nitrosourea (ENU) has been used since the 1970s in forward mutagenesis screens. However, only in the last decade has ENU mutagenesis been harnessed to generate a myriad of new mouse mutations in large-scale genetic screens and focused, smaller efforts....
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1197804/ https://ncbi.nlm.nih.gov/pubmed/16148305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MMBR.69.3.426-439.2005 |
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