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Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

The AKT family of serine threonine kinases is of critical importance with regard to growth factor signaling, cell proliferation, survival and oncogenesis. Engagement of signaling receptors induces the lipid kinase, phosphatidylinositol 3-kinase (PI3K), which enables the activation of AKT. Responsive...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Altomare, DA, Khaled, AR
Format: Artigo
Sprache:Inglês
Veröffentlicht: Bentham Science Publishers 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414727/
https://ncbi.nlm.nih.gov/pubmed/22680924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/092986712801661130
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