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Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

The AKT family of serine threonine kinases is of critical importance with regard to growth factor signaling, cell proliferation, survival and oncogenesis. Engagement of signaling receptors induces the lipid kinase, phosphatidylinositol 3-kinase (PI3K), which enables the activation of AKT. Responsive...

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Detalhes bibliográficos
Main Authors: Altomare, DA, Khaled, AR
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414727/
https://ncbi.nlm.nih.gov/pubmed/22680924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/092986712801661130
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