HuR’s post-transcriptional regulation of death receptor 5 in pancreatic cancer cells

Apoptosis is one of the core signaling pathways disrupted in pancreatic ductal adenocarcinoma (PDA). Death receptor 5 (DR5) is a member of the tumor necrosis factor (TNF)-receptor superfamily that is expressed in cancer cells. Binding of TNF-related apoptosis-inducing ligand (TRAIL) to DR5 is a pote...

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Main Authors: Pineda, Danielle M., Rittenhouse, David W., Valley, Christopher C., Cozzitorto, Joseph A., Burkhart, Richard A., Leiby, Benjamin, Winter, Jordan M., Weber, Matthew C., Londin, Eric R., Rigoutsos, Isidore, Yeo, Charles J., Gorospe, Myriam, Witkiewicz, Agnieska K., Sachs, Jonathan N., Brody, Jonathan R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Landes Bioscience 2012
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414415/
https://ncbi.nlm.nih.gov/pubmed/22785201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20952
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