HuR’s post-transcriptional regulation of death receptor 5 in pancreatic cancer cells

Apoptosis is one of the core signaling pathways disrupted in pancreatic ductal adenocarcinoma (PDA). Death receptor 5 (DR5) is a member of the tumor necrosis factor (TNF)-receptor superfamily that is expressed in cancer cells. Binding of TNF-related apoptosis-inducing ligand (TRAIL) to DR5 is a pote...

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Hlavní autoři: Pineda, Danielle M., Rittenhouse, David W., Valley, Christopher C., Cozzitorto, Joseph A., Burkhart, Richard A., Leiby, Benjamin, Winter, Jordan M., Weber, Matthew C., Londin, Eric R., Rigoutsos, Isidore, Yeo, Charles J., Gorospe, Myriam, Witkiewicz, Agnieska K., Sachs, Jonathan N., Brody, Jonathan R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2012
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414415/
https://ncbi.nlm.nih.gov/pubmed/22785201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20952
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