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PML body meets telomere: The beginning of an ALTernate ending?

The unlimited proliferation potential of cancer cells requires the maintenance of their telomeres. This is frequently accomplished by reactivation of telomerase. However, in a significant fraction of tumors an alternative lengthening of telomeres (ALT) mechanism is active. The molecular mechanism of...

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Autores principales: Chung, Inn, Osterwald, Sarah, Deeg, Katharina I., Rippe, Karsten
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414403/
https://ncbi.nlm.nih.gov/pubmed/22572954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.20326
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