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PML body meets telomere: The beginning of an ALTernate ending?

The unlimited proliferation potential of cancer cells requires the maintenance of their telomeres. This is frequently accomplished by reactivation of telomerase. However, in a significant fraction of tumors an alternative lengthening of telomeres (ALT) mechanism is active. The molecular mechanism of...

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Bibliografiske detaljer
Main Authors: Chung, Inn, Osterwald, Sarah, Deeg, Katharina I., Rippe, Karsten
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414403/
https://ncbi.nlm.nih.gov/pubmed/22572954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.20326
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