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PML body meets telomere: The beginning of an ALTernate ending?
The unlimited proliferation potential of cancer cells requires the maintenance of their telomeres. This is frequently accomplished by reactivation of telomerase. However, in a significant fraction of tumors an alternative lengthening of telomeres (ALT) mechanism is active. The molecular mechanism of...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Landes Bioscience
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3414403/ https://ncbi.nlm.nih.gov/pubmed/22572954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.20326 |
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