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Role of the inositol 1,4,5-trisphosphate receptor/Ca(2+)-release channel in autophagy

Autophagy is an important cell-biological process responsible for the disposal of long-lived proteins, protein aggregates, defective organelles and intracellular pathogens. It is activated in response to cellular stress and plays a role in development, cell differentiation, and ageing. Moreover, it...

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Bibliographic Details
Main Authors: Parys, Jan B, Decuypere, Jean-Paul, Bultynck, Geert
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413604/
https://ncbi.nlm.nih.gov/pubmed/22770472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-10-17
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