A novel cytarabine crystalline lipid prodrug: Hexadecyloxypropyl cytarabine 3′,5′-cyclic monophosphate for proliferative vitreoretinopathy

PURPOSE: The objectives of this study were to synthesize and characterize two types of cytarabine (Ara-C) lipid produgs and evaluate the prodrugs for sustained intraocular delivery after administration by intravitreal injection. METHODS: Hexadecyloxypropyl cytarabine 5′-monophosphate (HDP-P-Ara-C) a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kim, Jae Suk, Beadle, James R., Freeman, William R., Hostetler, Karl Y., Hartmann, Kathrin, Valiaeva, Nadejda, Kozak, Igor, Conner, Laura, Trahan, Julissa, Aldern, Kathy A., Cheng, Lingyun
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Molecular Vision 2012
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413433/
https://ncbi.nlm.nih.gov/pubmed/22876115
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