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Brown Remodeling of White Adipose Tissue by SirT1-Dependent Deacetylation of Pparγ
Brown adipose tissue (BAT) can disperse stored energy as heat. Promoting BAT-like features in white adipose (WAT) is an attractive, if elusive therapeutic approach to staunch the current obesity epidemic. Here we report that gain-of-function of the NAD-dependent deacetylase SirT1 or loss-of-function...
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| Autors principals: | , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413172/ https://ncbi.nlm.nih.gov/pubmed/22863012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.06.027 |
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