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Fgfr-Ras-MAPK signaling is required for apical constriction via apical positioning of Rho-associated kinase during mechanosensory organ formation

Many morphogenetic movements during development require the formation of transient intermediates called rosettes. Within rosettes, cells are polarized with apical ends constricted towards the rosette center and nuclei basally displaced. Whereas the polarity and cytoskeletal machinery establishing th...

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Библиографические подробности
Главные авторы: Harding, Molly J., Nechiporuk, Alex V.
Формат: Artigo
Язык:Inglês
Опубликовано: Company of Biologists 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413159/
https://ncbi.nlm.nih.gov/pubmed/22833124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.082271
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