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Fgfr-Ras-MAPK signaling is required for apical constriction via apical positioning of Rho-associated kinase during mechanosensory organ formation

Many morphogenetic movements during development require the formation of transient intermediates called rosettes. Within rosettes, cells are polarized with apical ends constricted towards the rosette center and nuclei basally displaced. Whereas the polarity and cytoskeletal machinery establishing th...

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Autors principals: Harding, Molly J., Nechiporuk, Alex V.
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413159/
https://ncbi.nlm.nih.gov/pubmed/22833124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.082271
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