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Apical constriction and invagination downstream of the canonical Wnt signaling pathway requires Rho1 and Myosin II
The tumor suppressor Adenomatous polyposis coli (APC) is a negative regulator of Wnt signaling and functions in cytoskeletal organization. Disruption of human APC in colonic epithelia initiates benign polyps that progress to carcinoma following additional mutations. The early events of polyposis are...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4056678/ https://ncbi.nlm.nih.gov/pubmed/20102708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2010.01.021 |
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