Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure

Cellular generation of mechanical forces required to close the presumptive spinal neural tube, the ‘posterior neuropore’ (PNP), involves interkinetic nuclear migration (INM) and apical constriction. Both processes change the apical surface area of neuroepithelial cells, but how they are biomechanica...

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Pubblicato in:J Cell Sci
Autori principali: Butler, Max B., Short, Nina E., Maniou, Eirini, Alexandre, Paula, Greene, Nicholas D. E., Copp, Andrew J., Galea, Gabriel L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Company of Biologists Ltd 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633395/
https://ncbi.nlm.nih.gov/pubmed/31182644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.230300
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