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Rho kinase-dependent apical constriction counteracts M-phase apical expansion to enable mouse neural tube closure

Cellular generation of mechanical forces required to close the presumptive spinal neural tube, the ‘posterior neuropore’ (PNP), involves interkinetic nuclear migration (INM) and apical constriction. Both processes change the apical surface area of neuroepithelial cells, but how they are biomechanica...

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Détails bibliographiques
Publié dans:J Cell Sci
Auteurs principaux: Butler, Max B., Short, Nina E., Maniou, Eirini, Alexandre, Paula, Greene, Nicholas D. E., Copp, Andrew J., Galea, Gabriel L.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists Ltd 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6633395/
https://ncbi.nlm.nih.gov/pubmed/31182644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.230300
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