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Fgfr-Ras-MAPK signaling is required for apical constriction via apical positioning of Rho-associated kinase during mechanosensory organ formation

Many morphogenetic movements during development require the formation of transient intermediates called rosettes. Within rosettes, cells are polarized with apical ends constricted towards the rosette center and nuclei basally displaced. Whereas the polarity and cytoskeletal machinery establishing th...

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Detalles Bibliográficos
Autores principales: Harding, Molly J., Nechiporuk, Alex V.
Formato: Artigo
Lenguaje:Inglês
Publicado: Company of Biologists 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413159/
https://ncbi.nlm.nih.gov/pubmed/22833124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.082271
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