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A rapid method for combined analysis of common and rare variants at the level of a region, gene, or pathway
Previously described methods for the combined analysis of common and rare variants have disadvantages such as requiring an arbitrary classification of variants or permutation testing to assess statistical significance. Here we propose a novel method which implements a weighting scheme based on allel...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3413013/ https://ncbi.nlm.nih.gov/pubmed/22888262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/AABC.S33049 |
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