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A Novel Approach for the Simultaneous Analysis of Common and Rare Variants in Complex Traits

Genome-wide association studies (GWAS) have been successful in detecting common genetic variants underlying common traits and diseases. Despite the GWAS success stories, the percent trait variance explained by GWAS signals, the so called “missing heritability” has been, at best, modest. Also, the pr...

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Detalhes bibliográficos
Main Authors: Yuan, Ao, Chen, Guanjie, Zhou, Yanxun, Bentley, Amy, Rotimi, Charles
Formato: Artigo
Idioma:Inglês
Publicado em: Libertas Academica 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273305/
https://ncbi.nlm.nih.gov/pubmed/22346348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S8852
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