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A Novel Approach for the Simultaneous Analysis of Common and Rare Variants in Complex Traits

Genome-wide association studies (GWAS) have been successful in detecting common genetic variants underlying common traits and diseases. Despite the GWAS success stories, the percent trait variance explained by GWAS signals, the so called “missing heritability” has been, at best, modest. Also, the pr...

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Autors principals: Yuan, Ao, Chen, Guanjie, Zhou, Yanxun, Bentley, Amy, Rotimi, Charles
Format: Artigo
Idioma:Inglês
Publicat: Libertas Academica 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3273305/
https://ncbi.nlm.nih.gov/pubmed/22346348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BBI.S8852
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