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Low magnitude mechanical signals mitigate osteopenia without compromising longevity in an aged murine model of spontaneous granulosa cell ovarian cancer

Cancer progression is often paralleled by a decline in bone mass, raising risk of fracture. Concerns persist regarding anabolic interventions for skeletal protection, as these may inadvertently exacerbate neoplastic tissue expansion. Given bone's inherent mechanosensitivity, low intensity vibra...

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Main Authors: Pagnotti, Gabriel, Adler, Benjamin J., Green, Danielle E., Chan, Meilin E., Frechette, Danielle, Shroyer, Kenneth R., Beamer, Wesley G., Rubin, Janet, Rubin, Clinton T.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412935/
https://ncbi.nlm.nih.gov/pubmed/22584009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2012.05.004
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