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High Fat Diet Rapidly Suppresses B Lymphopoiesis by Disrupting the Supportive Capacity of the Bone Marrow Niche

The bone marrow (BM) niche is the primary site of hematopoiesis, and cues from this microenvironment are critical to maintain hematopoiesis. Obesity increases lifetime susceptibility to a host of chronic diseases, and has been linked to defective leukogenesis. The pressures obesity exerts on hematop...

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Détails bibliographiques
Auteurs principaux: Adler, Benjamin J., Green, Danielle E., Pagnotti, Gabriel M., Chan, M. Ete, Rubin, Clinton T.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3942453/
https://ncbi.nlm.nih.gov/pubmed/24595332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090639
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